Boswellia, also known as Indian Frankincense, is a
traditional ayurvedic medicine that has been used for all sorts of conditions
from coughs and sores to snakebites and colic, and of course, it has also been
used as treatment for arthritis pain, as well. But does it really work? And is
there any basis for it working at all?
Generally speaking, these are the critical questions that
you must always ask when you are considering taking supplements, like
Boswellia, along with added questions of safety and interactions with any
current medications/medical conditions that you may be taking, so it's
important to always consult with your physician.
It appears that in the case of Boswellia, the answer seems
to be that it may in fact, be helpful to some degree with alleviation arthritis
pain, even though unlike most arthritis treatments (like NSAIDS for instance,
Boswella is neither an anti-pyretic (helps reduce fever) or an analgesic (helps
reduce pain topically like a mentholated cream).
Boswellic acid, which
is the major constituent, seems to have an anti-inflammatory effect, inhibiting
the production of several inflammatory cytokines such as NF-KB and TNF-alpha,
which are powerful cytokines that can produce fever, cell death, and sepsis. Likewise,
Boswella may help reduce the production of inflammatory molecules called
eicosinoids by inhibiting enzyme called 5-lipoxygenase. This may help relieve
the pain of osteoarthritis, (1) as eiconosoids modification can be helpful in
lessening the pain from arthritis. This is what Omega-3 fatty acids are thought
to do, that is they help modify the eiconsoids metabolism/milieu so it is more
generally anti-inflammatory.
Still, some skepticism should be applied, if not liberally,
as other studies have been less enthusiastic in proclaiming a pain relieving
effect. (2) In this study, ASU's (which are derived from soybean and avocado
oil) have been shown to be much more effective in the treatment of arthritis
pain, which is what I typically recommend for most patients, along with several other supplements and dietary strategies, to help attempt to naturally relieve
some of the symptoms of arthritis.
Is Boswella then right for you? Hard to say, really.
Although it does not appear to be harmful, it may not be all that helpful
compared to some of the other more well known and well-studied supplements
available, such as chondroitin, MSM, and glucosamine. That being said, it may be worthwhile to
consider this supplement (under your doctor's supervision is always preferable) if these other more
well known supplements fail to help relieve the pain you have.
References:
References:
Sengupta
K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo
controlled study of the efficacy and safety of 5-Loxin(R) for treatment of
osteoarthritis of the knee. Arthritis
Res Ther. Jul 30 2008;10(4):R85.
Chrubasik
JE, Roufogalis BD, Chrubasik S. Evidence of effectiveness of herbal
antiinflammatory drugs in the treatment of painful osteoarthritis and chronic
low back pain. Phytother
Res. Jul 2007;21(7):675-683.